Yes.  There were some issues with Vista when it first came out because we had not seen it to do any field testing.  Now if you do the latest update for the software from our website you will be able to run your BrainMaster with no problem.

You do NOT need to install WinDVD when using a Vista machine.  The DVD drivers are built in and seem to work fine. 

If you do run into an issue please let us know so we can correct it and make it available for other users.